Methods of preventing or treating recurrence of myocardial...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/55 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 31/325 (2006.01) A61K 31/4465 (2006.01) A61P 9/10 (2006.01) C07H 21/04 (2006.01) C12N 9/14 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2539276

Linkage of myocardial infarction (MI) with a locus on chromosome 12q23 is disclosed. In particular, the LTA4H gene within this locus is shown by association analysis to be a susceptibility gene for MI. Methods for preventing and/or treating the recurrence of MI, in particular are described.

L'invention concerne le lien entre l'infarctus du myocarde et un locus sur le chromosome 12q23. Plus précisément, une analyse par association fait apparaître que le gène LTA4H dans ce locus est un gène de susceptibilité à l'infarctus du myocarde. L'invention concerne en particulier des méthodes de prévention et/ou de traitement de la récurrence de l'infarctus du myocarde.

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