Methods of preventing viral replication

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/02 (2006.01) C12N 5/10 (2006.01) C12N 7/04 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2081022

2081022 9116420 PCTABS00008 The invention is drawn to methods and compositions for inhibiting viral replication. In particular, complete and irreversible termination of replication of a virus is achieved by introducing aT least one mutation at specific regions in the viral polymerase gene. The method can be used to prevent or treat viral infections.

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