Methods of producing a target molecule in a transgenic...

Details Methods of producing a target molecule in a transgenic... Methods of producing a target molecule in a transgenic...

A - Human Necessities

01

K

A01K 67/00 (2006.01) A01K 67/027 (2006.01) C07K 1/00 (2006.01) C07K 1/22 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01) C12P 21/06 (2006.01)

Patent

CA 2382741

The invention provides systems and methods for the production and purification of target molecules present in biological systems. The systems and methods according to the invention utilize transgenic expression of multivalent binding polypeptides, as affinity media, to purify such target molecules. The transgenic multivalent binding polypeptides bind both the target molecules, e.g., a bindable epitope of a target molecule, and a matrix.

L'invention concerne des systèmes et des méthodes de production et de purification de molécules cibles présentes dans des systèmes biologiques. Les systèmes et les méthodes de l'invention utilisent l'expression transgénique de polypeptides de fixation multivalents, en tant que supports d'affinité, pour purifier lesdites molécules cibles. Les polypeptides de fixation multivalents transgéniques fixent à la fois les molécules cibles, par exemple, un épitope fixable d'une molécule cible, et une matrice.

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