Methods of producing cloned and transgenic mammals

Details Methods of producing cloned and transgenic mammals Methods of producing cloned and transgenic mammals

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) A01N 63/00 (2006.01) A61K 48/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2385015

The invention features a method of promoting the development of a pre-natal non-human mammal. The method includes: forming a reconstructed embryo in association with at least one extra embryonic cell, e.g., a tetraploid cell; transferring the reconstructed embryo into a recipient mammal; and allowing the embryo to develop, to thereby promote development of the mammal.

Ce procédé, destiné à favoriser le développement d'un mammifère non humain prénatal, comprend les étapes suivantes consistant: à former un embryon reconstruit en association avec au moins une cellule extra-embryonnaire, par exemple une cellule tétraploïde, à transférer l'embryon reconstruit dans un mammifère récepteur, et à permettre à l'embryon de se développer, afin de favoriser le développement du mammifère.

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