Methods of production and use of liquid formulations of...

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) A61K 35/16 (2006.01) A61K 38/37 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2239206

The present invention relates to the preparation and use of liquid formulation of plasma proteins, particularly blood coagulation factors. More specifically, the present invention relates to stable liquid formulations of Factor VIII and Factor IX that can be administered by injection or infusion to provide a constant level of the coagulation factor in the blood.

La présente invention concerne la préparation et l'utilisation d'une formulation liquide de protéines plasmatiques, en particulier des facteur de coagulation sanguine. Plus précisément, cette invention porte sur des formulations liquides stables de facteur VIII et de facteur IX qui peuvent être administrées par injection ou perfusion de façon à ce que la concentration sanguine du facteur de coagulation en cause demeure stable.

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