Methods of propagation of influenza virus in cell lines over...

Details Methods of propagation of influenza virus in cell lines over... Methods of propagation of influenza virus in cell lines over...

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A61K 39/145 (2006.01) C07K 14/11 (2006.01) C12N 5/22 (2006.01) C12N 7/04 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2468957

The invention provides means, methods and use for producing a virus particle, including cells therefore and virus particles thus produced. One aspect of the invention utilizes cells provided with nucleic acid encoding post- translational modification protein, thereby altering at least one property of virus (being) produced by the cells compared to the un-manipulated cell.

L'invention concerne des moyens et des procédés de production et d'utilisation d'une particule virale et des cellules de cette particule. L'invention concerne également les particules virales ainsi produites. Dans un aspect de la présente invention, on utilise des cellules contenant un acide nucléique codant pour une protéine de modification post-translationnelle, ce qui permet de modifier au moins une propriété du virus produit par ces cellules, résultat qui ne pourrait être obtenu au moyen de cellules non manipulées.

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