A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 9/19 (2006.01) C07K 14/505 (2006.01)
Patent
CA 2704598
The present invention relates, in general, to a method of purifying recombinant human erythropoietin (EPO). The present invention also relates to a substantially pure EPO. The method comprises a differential precipitation, an hydrophobic interaction chromatography, various concentration and diafiltration steps, tandem anionic and cationic exchange chromatographies and molecular exclusion chromatography for the obtaining of pure EPO. The method does not comprise high performance liquid chromatography steps. The invention also comprises the EPO obtained according to the claimed procedure.
Carcagno Carlos Miguel
Criscuolo Marcelo
Melo Carlos
Vidal Juan Alejandro
Mbm Intellectual Property Law Llp
Sterrenbeld Biotechnologie North America Inc.
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