Methods of reducing apolipoprotein e4-induced inhibition of...

Details Methods of reducing apolipoprotein e4-induced inhibition of... Methods of reducing apolipoprotein e4-induced inhibition of...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61K 38/40 (2006.01) C07K 16/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2233848

The present invention provides methods of reducing apolipoprotein E4 (apoE4) induced inhibition of neuron remodeling. The methods include preventing apoE4 from interacting effectively with neuronal low density lipoprotein receptor-related protein.

Sont décrites dans la présente invention des méthodes visant à réduire l'inhibition du remaniement neuronal induite par l'apolipoprotéine E4 (apoE4). Les méthodes empêchent notamment l'apoE4 d'interagir efficacement avec la protéine liée aux récepteurs neuronaux des lipoprotéines de basse densité.

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