Methods of reducing phosphate absorption

Details Methods of reducing phosphate absorption Methods of reducing phosphate absorption

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) A61K 39/395 (2006.01) A61P 3/12 (2006.01) A61P 13/12 (2006.01)

Patent

CA 2667563

It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-intestinal alkaline phosphatase antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.

L'invention concerne un procédé pour réduire l'absorption de phosphate chez un sujet humain ou animal, le sujet suivant un régime contenant de l'acide phytique ou un phytate, et ayant ou risquant de développer une hyperphosphatémie. Le procédé comprend l'étape consistant à administrer oralement au sujet un anticorps de phosphatase alcaline anti-intestinale, en une quantité efficace pour réduire ou maintenir la concentration en phosphate sérique chez le sujet.

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