Methods of reducing serum glucose and triglyceride levels...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/404 (2006.01) A61K 31/00 (2006.01) A61K 31/405 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/14 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2385845

Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.

L'invention concerne des techniques permettant de réduire les taux de glucose sérique et de triglycérides et d'inhiber l'angiogénèse. Ces techniques consistent à administrer des acides indoléalcanoiques substitués aux patients nécessitant ce traitement. L'invention concerne également des composés utiles dans le traitement de l'angiogénèse, de l'hyperglycémie, de l'hyperlipidémie et des complications chroniques dues aux diabètes sucrés. L'invention concerne, en outre, des compositions pharmaceutiques contenant lesdits composés.

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