C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) C07K 14/71 (2006.01) G01N 23/20 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01) G06F 17/40 (2006.01) G06F 19/00 (2006.01) G06N 5/00 (2006.01)
Patent
CA 2456236
This invention relates to the structure of members of the epidermal growth factor (EGF) receptor family and to receptor/ligand interactions. In particular, it relates to the field of using the EGF receptor family structure to select and screen for compounds that inhibit the formation of active receptor dimers.
La présente invention concerne la structure d'éléments de la famille du récepteur du facteur de croissance épidermique (EGF), ainsi que des interactions récepteur/ligand. Plus particulièrement, la présente invention concerne l'utilisation de la structure de la famille du récepteur EGF pour sélectionner et cribler des composés inhibant la formation de dimères actifs du récepteur.
Adams Timothy Edward
Burgess Antony Wilks
Elleman Thomas Charles
Garrett Thomas Peter John
Jorissen Robert Nicholas
Commonwealth Scientific And Industrial Research Organisation
Ludwig Institute For Cancer Research
Smart & Biggar
Walter And Eliza Hall Institute Of Medical Research
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