Methods of searching for solid forms and screening a sample...

Details Methods of searching for solid forms and screening a sample... Methods of searching for solid forms and screening a sample...

C - Chemistry, Metallurgy

30

B

C30B 7/00 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2433385

Methods for searching for possible forms of a sample and methods of screening a sample according to its form comprise disposing the sample in at least one receptacle that defines a capillary space, such as a capillary tube; The sample is solidified to generate at least one solid form or semisolid form, and the generated form is analyzed and classified. The analysis may determine differences in molecular arrangement of the various forms or characteristics that reflect the form. The methods may employ a plurality of samples, conditions, or receptacles in an effort to generate a variety of forms, so that all or a high percentage of possible forms are obtained.

L'invention porte sur des procédés de recherche de toutes les formes possibles que peut prendre un échantillon et sur des procédés de criblage d'un échantillon en fonction de sa forme, consistant à placer un tel échantillon dans un réceptacle incluant un espace capillaire, tel qu'un tube capillaire. L'échantillon est solidifié pour produire au moins une forme solide ou semi-solide, puis la forme ainsi créée est analysée et classée. L'analyse peut déterminer les différences entre les arrangements moléculaires des différentes formes ou les caractéristiques propres à une forme. Ces procédés peuvent utiliser différents échantillons, états ou réceptacles dans le but de créer des formes très variées de manière à obtenir toutes les formes possibles, ou au moins une grande partie d'entre elles.

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