Methods of selecting compounds for modulation of bladder...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/02 (2006.01) A61K 31/24 (2006.01) A61K 31/405 (2006.01) A61K 38/00 (2006.01) A61K 45/08 (2006.01) A61P 13/10 (2006.01) C07K 14/705 (2006.01) C12N 15/79 (2006.01) G01N 21/64 (2006.01) G01N 27/00 (2006.01) G01N 27/26 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2425742

The present invention involves an assay system and method of selecting compounds useful in the treatment of bladder instability and related bladder conditions through the activation of KCNQ potassium channels in the bladder smooth muscle.

La présente invention traite d'un système d'analyse et d'un procédé de sélection de composés utiles dans le traitement de l'instabilité vésicale et d'états vésicaux associés, par le biais de l'activation de canaux potassiques KCNQ dans le muscle lisse de la vessie.

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