Methods of sterilizing biological materials containing...

A - Human Necessities – 61 – L

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A61L 2/08 (2006.01) A61K 39/395 (2006.01) A61L 2/00 (2006.01) A61L 2/10 (2006.01) A61L 2/16 (2006.01) C07K 16/26 (2006.01)

Patent

CA 2460644

Methods are disclosed for sterilizing biological materials to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing biological materials containing one or more non-aqueous solvents with irradiation.

L'invention concerne des procédés de stérilisation de matières biologiques conçus pour réduire le taux d'un ou plusieurs contaminants biologiques actifs ou pathogènes présents dans lesdites matières, tels que des virus, des bactéries (notamment des bactéries intercellulaires et intracellulaires, telles que des mycoplasmes, des uréaplasmes, des nanobactéries, des chlamydias, des rickettsies), des levures, des moisissures, des champignons, des prions ou des agents similaires responsables, seuls ou en combinaison, des EST et/ou des parasites unicellulaires ou multicellulaires. Lesdits procédés consistent à stériliser par irradiation des matériaux biologiques contenant un ou plusieurs solvants non aqueux.

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