Methods of stimulating phagocytosis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/56 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01) A61K 48/00 (2006.01) C07K 14/735 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2172393

The present invention relates, in general, to methods of stimulating phagocytosis and thereby combating infection and/or modulating immune complex disease, in particular, to methods of modulating the number and type of Fc receptors present on cells that normally possess such receptors, including monocytes and macrophages, as well as on cells that normally do not possess Fc receptors, such as fibroblasts, and to compounds and compositions suitable for use in such methods.

L'invention porte d'une façon générale sur des méthodes de stimulation de la phagocytose et ainsi de lutte contre des infections et/ou de modulation d'affections immunes complexes , et en particulier sur des méthodes de modulation du nombre et du type de récepteurs du fragment Fc présents dans des cellules qui possèdent normalement de tels récepteurs, y compris des monocytes et des macrophages, ainsi que sur des cellules ne possédant pas normalement de tels récepteurs, telles que les fibroblastes , et sur des composés et compositions susceptibles d'être utilisés avec ces méthodes.

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