Methods of supressing uv light-induced skin carcinogenesis

Details Methods of supressing uv light-induced skin carcinogenesis Methods of supressing uv light-induced skin carcinogenesis

A - Human Necessities

61

K

A61K 31/095 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2606382

ABSTRACT Administration of the isothiocyanate protects against UV light- induced skin carcinogenesis. In particular, topical application or dietary administration of isothiocyanate sulforaphane after exposure to UV radiation provides effective protection against skin tumor formation. Sulforaphane analogs and glucosinolates also can be employed. Lotions useful for suppressing UV light-induced skin carcinogenesis also are provided.

L'administration de l'isothiocyanate assure la protection contre la carcinogenèse de la peau induite par les UV. Plus particulièrement, l'application topique ou l'administration par voie orale du sulforaphane isothiocyanate après exposition aux rayons UV assure une protection efficace contre la formation de tumeurs cutanées. Les analogues de sulforaphane et les glucosinolates peuvent également être utilisés. Des lotions s'avèrent également utiles pour traiter la carcinogenèse de la peau induite par les UV.

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