Methods of synthesizing and screening inhibitors of...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A01N 43/38 (2006.01) A01N 43/40 (2006.01) A01N 43/42 (2006.01) A61K 31/40 (2006.01) C07C 229/42 (2006.01) C07C 235/46 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 209/42 (2006.01) C07D 213/80 (2006.01) C07D 401/06 (2006.01) C12Q 1/48 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2317439

The present invention provides methods of synthesizing and screening inhibitors of bacterial NAD synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial NAD synthetase enzyme.

L'invention concerne des procédés qui permettent d'assurer la synthèse et le criblage d'inhibiteurs de l'enzyme synthétase NAD. L'invention concerne également des composés à base de cette enzyme et des procédés de traitement des infections bactériennes et microbiennes au moyen d'inhibiteurs de ladite enzyme.

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