C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2508580
Targeting of Ly-9 expressing cells using targeting compounds such as Ly-9 polypeptides, nucleic acids encoding for Ly-9 polypeptides and anti-Ly-9 antibodies provides a method of killing or inhibiting growth of said cells that may be useful in treating diseases including cancer. Methods of therapy and diagnosis of disorders associated with Ly-9-protein-expressing cells are described.
La présente invention a trait au ciblage de cellules d'expression de Ly-9 au moyen de composés de ciblage tels que des polypeptides Ly-9, des acides nucléiques codant pour des polypeptides Ly-9 et des anticorps fournissant un procédé d'élimination et d'inhibition de la croissance desdites cellules qui peuvent utiles dans le traitement de maladies y compris le cancer. L'invention a également trait à des procédés de thérapie et de diagnostic de troubles associés aux cellules d'expression de protéines Ly-9.
Nuvelo Inc.
Smart & Biggar
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