Methods of treating alzheimer's disease

Details Methods of treating alzheimer's disease Methods of treating alzheimer's disease

A - Human Necessities

61

K

A61K 31/535 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/54 (2006.01) A61K 31/66 (2006.01) A61K 31/7068 (2006.01) A61K 45/06 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2449948

Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of hydrazine compounds of formula (I) wherein the variables R1-R9 are defined herein.

La présente invention concerne des procédés permettant le traitement de la maladie d'Alzheimer et d'autres maladies, et/ou l'inhibition de l'enzyme bêta-sécrétase, et/ou l'inhibition du dépôt de peptide A bêta chez un mammifère, par utilisation de composés d'hydrazine de formule (I) dans laquelle les variables R¿1?-R¿9? sont telles que définies dans la description.

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