A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01)
Patent
CA 2547963
The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration of one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA. Preferably the pharmaceutical composition comprises one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, an anti-inflammatory agent, and a pharmaceutically acceptable carrier.
L'invention concerne des compositions pharmaceutiques et des méthodes permettant de traiter les pathologies de type inflammatoire associées à une expression de cytokines pro-inflammatoires et/ou à une expression réduite de cytokines anti-inflammatoires. La méthode décrite comprend en général l'administration d'un ou de plusieurs composés choisi parmi isoindigo, indigo, indirubine, ou des dérivés de ceux-ci, tels que Meisoindigo et NATURA. La composition pharmaceutique comprend de préférence un ou plusieurs composés choisis parmi isoindigo, indigo, indirubine, ou des dérivés de ceux-ci, un agent anti-inflammatoire et un excipient pharmaceutiquement acceptable.
Liu Xiao Mei
Mccarron James P. Jr.
Mencher Simon K.
Mo Lian
Wang Longgui
Gowling Lafleur Henderson Llp
Natrogen Therapeutics Inc.
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