A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 1/00 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/04 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 45/00 (2006.01) A61P 1/04 (2006.01) G01N 33/15 (2006.01) G06G 7/48 (2006.01)
Patent
CA 2489540
Method of treating or preventing the inflammatory response of colitis in a subject comprising administering to the subject an effective amount of a substance that modulates IL-13 activity (figure 3). The invention also provides a method of treating or preventing the inflammatory response of colitis in a subject comprising administering to the subject an effective amount of a substance that modulates NK-T cell activity. The invention also provides for the screening of substances that treat or prevent the inflammatory response of colitis.
L'invention concerne un procédé de traitement et de prévention de la réponse inflammatoire d'une colite chez un sujet, lequel consiste à administrer au sujet une quantité efficace d'une substance qui module l'activité de l'interleukine 13. L'invention concerne également un procédé de traitement et de prévention de la réponse inflammatoire d'une colite chez un sujet, lequel consiste à administrer au sujet une quantité efficace d'une substance qui module l'activité des cellules NK-T. De plus, l'invention concerne le criblage de substances qui traitent ou préviennent la réponse inflammatoire d'une colite.
Blumberg Richard
Fuss Ivan J.
Heller Frank
Strober Warren
Dept. Of Health And Human Services Office Of Technology Transfe The Government Of The United States Of America As Represented By
Gowling Lafleur Henderson Llp
The Brigham And Women's Hospital Inc
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