Methods of treating bacterial infections using oritavancin

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/16 (2006.01) A61K 31/35 (2006.01) A61P 31/00 (2006.01) C12P 17/16 (2006.01) C12Q 1/18 (2006.01)

Patent

CA 2760159

The present invention is directed to methods of treating a bacterial infection in a subject through the administration of a therapeutically effective amount of a glycopeptide antibiotic to a subject having a bacterial infection. The effective amount of the glycopeptide antibiotic that is administered to the subject provides a fraction of the glycopeptide antibiotic administered to the subject bound to serum proteins within the subject and within a selected range.

La présente invention porte sur des procédés de traitement d'une infection bactérienne chez un sujet par l'administration d'une quantité thérapeutiquement efficace d'un antibiotique glycopeptidique à un sujet atteint d'une infection bactérienne. La quantité efficace de l'antibiotique glycopeptidique qui est administré au sujet fournit une fraction de l'antibiotique glycopeptidique administré au sujet lié aux protéines du sérum à l'intérieur du sujet et à l'intérieur d'une plage choisie.

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