A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 38/20 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2681827
The present invention relates generally to the use of human IL- 18 combinations in the treatment of various forms of solid tumors and lymphomas. In particular, the present invention relates to: (1) combinations of human IL-18 with monoclonal antibodies against antigens that are expressed on the surface of cancer cells; and (2) combinations of human IL- 18 with chemotherapeutic agents.
La présente invention concerne d'une manière générale l'utilisation de l'IL-18 humaine en combinaison dans le traitement de diverses formes de tumeurs solides et de lymphomes. Cette invention concerne en particulier (1) l'utilisation de l'IL-18 humaine combinée à des anticorps monoclonaux dirigés contre des antigènes exprimés sur la surface de cellules cancéreuses; et (2) l'utilisation de l'IL-18 humaine combinée à des agents chimiothérapeutiques.
Haskova Zdenka
Jonak Zdenka Ludmila
Trulli Stephen H.
Whitacre Margaret N.
Glaxosmithkline Llc
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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