Methods of treating capsules and dry, powdered...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61J 3/07 (2006.01) A61K 9/14 (2006.01) A61K 31/137 (2006.01) A61K 31/46 (2006.01) A61K 31/57 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2302276

Undesirable materials present in gelatin, cellulose or plastic capsules used for storing a dry, powdered pharmaceutical formulation are extracted by supercritical fluids. The method is also used for removing undesirable material from drug powder. The amount of powder retained in the capsules following inhalation is minimized.

On extrait des matériaux indésirables présents dans des capsules en gélatine, en cellulose ou en plastique utilisées afin de contenir une formulation pharmaceutique sèche et pulvérulente, au moyen de fluides supercritiques. On met également en application ce procédé afin d'extraire des matériaux indésirables hors de médicaments en poudre. Ceci permet de limiter au maximum la quantité de poudre retenue dans les capsules après inhalation.

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