Methods of treating demyelinating disorders

Details Methods of treating demyelinating disorders Methods of treating demyelinating disorders

G - Physics

01

N

G01N 33/53 (2006.01)

Patent

CA 2565043

Methods of identifying and using compounds capable of treating demyelinating disorders such as multiple sclerosis by inhibiting EphB1-mediated cell repulsion of CNS and PNS glial cells (oligodendrocytes and Schwann cells and progenitor cells within these lineages).

L'invention concerne des méthodes d'identification et d'utilisation de composés permettant de traiter des troubles de démyélinisation tels que la sclérose en plaques par inhibition de la répulsion cellulaire induite par l'EphB1 de cellules gliales du SNC et du SNP (oligodendrocytes et cellules de Schwann ainsi que cellules progénitrices dans lesdites lignées).

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