Methods of treating diabetes by blocking vegf-mediated activity

Details Methods of treating diabetes by blocking vegf-mediated activity Methods of treating diabetes by blocking vegf-mediated activity

A - Human Necessities

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A61K 48/00 (2006.01) A61K 31/19 (2006.01) A61K 31/70 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) A61P 3/10 (2006.01) C07K 14/52 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2519787

Methods of treating diabetes in mammals, particularly humans, by blocking or inhibiting VEGF-mediated activity. A preferred inhibitor of VEGF-mediated activity is a VEGF antagonist such as a VEGF trap capable of binding and blocking VEGF.

L'invention concerne des méthodes permettant de traiter le diabète chez des mammifères, notamment chez l'homme, par blocage ou inhibition de l'activité induite par le facteur de croissance endothéliale. Un inhibiteur préféré de l'activité induite par le facteur de croissance endothéliale est un antagoniste du facteur de croissance endothéliale, tel qu'un piège du facteur de croissance endothéliale apte à fixer et à bloquer le facteur de croissance endothéliale.

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