A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4196 (2006.01) A61K 31/4439 (2006.01) A61K 31/5377 (2006.01) A61K 31/7088 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2546360
The present invention is directed to the use of single agents, which are compounds that target two or more kinases simultaneously, thus substantially avoiding resistance to therapy. The invention provides methods for the use for, administration to, and treatment of individuals having a variety of diseases or conditions associated with the activity of two or more kinases, comprising administration of one or more single agents, either alone or in combination with other therapies for the same disease or condition.
La présente invention a trait à l'utilisation d'agents de monothérapie, qui sont des composés de ciblage simultané d'au moins deux kinases, permettant ainsi d'éviter sensiblement la résistance à la thérapie. L'invention a trait à des procédés pour l'utilisation, l'administration, et le traitement d'individus souffrant de diverses maladies ou conditions associées à l'activité d'au moins deux kinases, comprenant l'administration d'un ou de plusieurs agents de monothérapie, seuls ou en combinaison avec d'autres thérapies pour la même maladie ou condition.
Narla Rama K.
Sakata Steven T.
Osler Hoskin & Harcourt Llp
Signal Pharmaceuticals Llc
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