A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/24 (2006.01) C12Q 1/00 (2006.01) G01N 33/48 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2235866
The present invention provides a method for treating the inflammatory response of an established colitis in a subject with inflammatory bowel disease (IBD) comprising administering to a subject diagnosed with an established colitis from an IBD an amount of an antibody to interleukin-12 effective in reducing the colitis-inducing effect of interleukin-12. Also provided is a method for screening a substance for its effectiveness in reducing the inflammatory response of an established colitis. Additionally, the present invention provides a method for screening a substance for its effectiveness in preventing inflammatory bowel disease.
La présente invention concerne un traitement visant à atténuer la réaction inflammatoire associée à une colite chronique chez les sujets atteints d'une maladie inflammatoire intestinale, lequel traitement consiste à administrer une quantité efficace d'un anticorps anti-interleukine-12 à des sujets chez qui on a diagnostiqué une colite chronique due à une maladie inflammatoire intestinale, ce qui permet de réduire l'effet inducteur de colite de l'interleukine-12. L'invention concerne également un procédé de criblage visant à déterminer l'efficacité de diverses substances dans l'atténuation de la réaction inflammatoire associée à une colite chronique. La présente invention concerne enfin un procédé de criblage visant à déterminer l'efficacité de diverses substances dans la prévention des maladies intestinales inflammatoires.
Fuss Ivan
Neurath Markus
Strober Warren
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Gowling Lafleur Henderson Llp
LandOfFree
Methods of treating established colitis using antibodies... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of treating established colitis using antibodies..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of treating established colitis using antibodies... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1549408