Methods of treating fungal infections with inhibitors of nad...

Details Methods of treating fungal infections with inhibitors of nad... Methods of treating fungal infections with inhibitors of nad...

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/216 (2006.01) A61K 31/235 (2006.01) A61K 31/343 (2006.01) A61K 31/404 (2006.01) A61K 31/4406 (2006.01) A61K 31/4425 (2006.01) A61K 31/443 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/4745 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2376892

The present invention provides methods of treating or preventing fungal infections in a host comprising administering a treatment effective or treatment effective amount of a yeast NAD synthetase inhibitor compound. The invention further provides a method of killing yeast comprising administring a yeast NAD synthetase compound that selectively binds to catalytic sites in yeast whereby the yeast is killed.

L'invention concerne des techniques de traitement ou de prévention des infections fongiques chez un hôte, consistant à administrer un traitement efficace ou une quantité de traitement efficace d'un composé inhibiteur de NAD-synthétase de levure. L'invention concerne également une technique permettant de détruire des levures, consistant à administrer un composé de NAD-synthétase qui se lie sélectivement à des sites catalytiques de levures, ce qui assure la destruction desdites levures.

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