A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7076 (2006.01) A61P 35/02 (2006.01) G01N 33/68 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2596543
The present invention provides methods of treating hematological malignancies, including multi-drug resistant malignancies, with 8-amino-adenosine and variants thereof. Also encompassed by the present invention is a method of predicting the response of a patient diagnosed with a hematological malignancy to treatment with a nucleoside analog and a method of screening candidate drugs for efficacy in treating hematological malignancies.
L'invention concerne des méthodes permettant de traiter des malignités hématologiques, notamment des malignités résistant à plusieurs médicaments, à l'aide de 8-amino-adénosine et des variantes de celle-ci. L'invention concerne également une méthode permettant de prédire la réponse d'un patient souffrant d'une malignité hématologique à un traitement à l'aide d'un analogue nucléosidique et une méthode permettant de cribler des médicaments candidats destinés à traiter efficacement des malignités hématologiques.
Gandhi Varsha
Ghias Kulsoom
Krett Nancy L.
Ma Chunguang
Platanias Leonidas C.
Northwestern University
Sim & Mcburney
The Board Of Regents Of The University Of Texas System
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