A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/675 (2006.01) A61K 31/7068 (2006.01) A61K 38/21 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) A61K 49/06 (2006.01) G01N 33/564 (2006.01)
Patent
CA 2641513
Natalizumab is a safe and efficacious treatment for inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, and rheumatoid arthritis. Rare occurrences of progressive multifocal leucoencephalopathy during treatment suggest the possibility that it may be related to natalizumab treatment. Monitoring for JCV and informing caregivers and patients about the manifestations of progressive multifocal leucoencephalopathy can improve the safety of natalizumab therapy.
Selon l'invention, le natalizumab est un traitement sûr et efficace pour des maladies inflammatoires et auto-immunes, telles que la sclérose en plaques, la maladie de Crohn et la polyarthrite rhumatoïde. De rares cas de leucoencéphalopathie multifocale progressive durant le traitement suggèrent un rapport avec le traitement au natalizumab. La surveillance du virus JC et l'information du personnel soignant et des patients concernant les manifestations de la leucoencéphalopathie multifocale progressive peuvent améliorer l'innocuité de la thérapie au natalizumab.
Lieberburg Ivan
Elan Pharmaceuticals Inc.
Kirby Eades Gale Baker
LandOfFree
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