A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/48 (2006.01) A61P 3/00 (2006.01)
Patent
CA 2693254
The present invention is directed to a method of simultaneously treating hypertension, hypertriglyceridemia, a pro-inflammatory state, a pro-coagulative state, and insulin resistance (with or without treating obesity or endothelial dysfunction), associated with or independent from Metabolic Syndrome, as well as vascular disease such as cardiovascular, cerebrovascular, or peripheral vascular disease comprising the step of administering to a patient suffering from such disorders a therapeutically effective amount of a central acting dopamine agonist. In one embodiment, the central acting dopamine agonist is bromocriptine, optionally combined with a pharmaceutically acceptable carrier.
L'invention concerne un procédé pour traiter simultanément l'hypertension, l'hypertriglycéridémie, un état pro-inflammatoire, un état pro-coagulation et une résistance à l'insuline (avec ou sans traitement de l'obésité ou d'un dysfonctionnement endothélial), associé(e) au syndrome métabolique ou indépendant de celui ci, de même qu'une maladie vasculaire comme une maladie cardio-vasculaire, cérébrovasculaire ou une maladie vasculaire périphérique. Ledit procédé comporte l'étape consistant à administrer à un patient souffrant de tels troubles une quantité thérapeutiquement efficace d'un agoniste de dopamine à action centrale. Dans un mode de réalisation, l'agoniste de dopamine à action centrale est de la bromocriptine combinée facultativement avec un support pharmaceutiquement acceptable.
Smart & Biggar
Veroscience Llc
LandOfFree
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