A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7048 (2006.01) A61K 38/21 (2006.01) A61K 38/22 (2006.01) A61P 35/00 (2006.01) C12N 15/861 (2006.01)
Patent
CA 2404060
The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.
Cette invention concerne des méthodes de traitement de la néoplasie avec des vecteurs adénoviraux spécifiques des cellules cibles capables de réplication, associés à la chimiothérapie ou à la radiothérapie, ou leurs combinaisons. Les vecteurs adénoviraux sont spécifiques des cellules cibles pour le type particulier de néoplasie pour lequel le traitement est nécessaire, et la chimiothérapie et/ou la radiothérapie combinées fournissent un traitement synergique relativement aux thérapies adénovirales existantes ou aux chimiothérapies et radiothérapies classiques.
Chen Yu
Henderson Daniel R.
Yu De-Chao
Cell Genesys Inc.
Fetherstonhaugh & Co.
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