C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 5/00 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2373797
The invention is directed to compositions comprising, and methods of using, racemic N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (-)-N-desmethylzopiclone in the treatment and prevention of diseases and conditions in mammals. The invention is further directed to novel methods of preparing N- desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (-)-N-desmethylzopiclone.
La présente invention concerne des compositions contenant, et des procédés d'utilisation, du N-desméthylzopiclone racémique, du (+)-N-desméthylzopiclone optiquement pur, et du (-)-N-desméthylzopiclone optiquement pur pour le traitement et la prévention de maladies et de conditions chez les mammifères. L'invention concerne également de nouveaux procédés de préparation de N-desméthylzopiclone, du (+)-N-desméthalzopiclone optiquement pur, et du (-)-N-desméthylzopiclone optiquement pur.
Bakale Roger P.
Hong Yaping
Jerussi Thomas P.
Mcconville Fran A.
Rubin Paul D.
Osler Hoskin & Harcourt Llp
Sepracor Inc.
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