Methods of treating or preventing cell, tissue, and organ...

Details Methods of treating or preventing cell, tissue, and organ... Methods of treating or preventing cell, tissue, and organ...

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61K 38/16 (2006.01) A61K 41/00 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2387545

There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine .beta.8 (CK.beta.8 or ckb-8)), as well as MPIF-1 polypeptide itself, as are vectors, host cells and recombinant methods for producing the same.

L'invention concerne des compositions et des méthodes thérapeutiques utilisant des molécules d'acides nucléiques isolées codant un polypeptide du facteur-1 inhibiteur des précurseurs myéloïdes (MPIF-1) d'origine humaine (précédemment appelé MIP-3 et chimiokine .beta.8 (CK.beta.8 ou ckb-8)), ainsi que ce polypeptide MPIF-1 lui-même, des vecteurs, des cellules hôtes et des méthodes de recombinaison destinées à la production de MPIF-1.

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