Methods of treating proliferative disorders

Details Methods of treating proliferative disorders Methods of treating proliferative disorders

A - Human Necessities

61

K

A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2384287

Disclosed are methods and compositions for treating proliferative disorders, such as cancers, blood vessel disorders, fibrotic disorders and acute or chronic rejection of transplanted organs, tissue or cells, using compounds of formula (I) or a tautomeric isomer thereof wherein R1 and R2 are as defined; or a pharmaceutically-acceptable salt or pro-drug thereof.

L'invention concerne des méthodes et des compositions de traitement de troubles prolifératifs, tels que les cancers, les lésions connexes des vaisseaux sanguins, les troubles fibreux, ainsi que les rejets chroniques et les crises de rejet d'organes, de tissus ou de cellules, à partir de composés de formule (I), ou d'un isomère tautomère desdits composés, dans laquelle R?1¿ et R?2¿ sont tels que définis; ou d'un sel ou médicament acceptable sur le plan pharmaceutique desdits composés.

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