A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7088 (2006.01) A61K 31/155 (2006.01) A61K 31/20 (2006.01) A61K 31/336 (2006.01) A61K 31/34 (2006.01) A61K 48/00 (2006.01) C07K 16/44 (2006.01) C12Q 1/34 (2006.01)
Patent
CA 2262525
The present invention provides methods of treating inflammatory diseases mediated by polyunsaturated lipid metabolites by inhibiting epoxide hydrolase, methods for assaying or screening the epoxide hydrolase inhibitors for inhibitory specificity and for toxicity, and novel biologically active tetrahydrofuran diols of arachidonic acid, including antibodies thereto.
La présente invention propose des méthodes de traitement des affections inflammatoires induites par des métabolites lipidiques poly-insaturés, par inhibition de l'hydrolase d'époxyde, des méthodes de dosage ou de criblage des inhibiteurs de l'hydrolase d'époxyde en fonction de leur spécificité inhibitrice et de leur toxicité, ainsi que de nouveaux diols biologiquement actifs de tétrahydrofurane de l'acide arachidonique, ainsi que leurs anticorps.
Borhan Babak
Cheek Jeffrey M.
Fergusson James
Grant David F.
Greene Jessica F.
Smart & Biggar
The Regents Of The University Of California
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