Methods of treatment using anti-mif antibodies

Details Methods of treatment using anti-mif antibodies Methods of treatment using anti-mif antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 39/00 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2717071

Disclosed herein, in certain embodiments, is a method for treating an inflammatory disorder. In some embodi-ments, the method comprises administering an active agent that inhibits (i) MIF binding to CXCR2 and CXCR4 and/or (ii) MIF--activation of CXCR2 and CXCR4; (iii) the ability of MIF to form a homomultimer; or a combination thereof.

L'invention concerne, dans certains modes de réalisation, un procédé permettant de traiter un trouble inflammatoire. Dans un certain nombre de modes de réalisation, le procédé consiste à administrer un agent actif qui inhibe (i) la liaison de MIF à CXCR2 et CXCR4 et/ou (ii) l'activation de MIF de CXCR2 et CXCR4; (iii) l'aptitude de MIF à former un homomultimère; ou une combinaison de ceux-ci.

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