Methods of treatment using unilamellar liposomal arachidonic...

Details Methods of treatment using unilamellar liposomal arachidonic... Methods of treatment using unilamellar liposomal arachidonic...

A - Human Necessities

61

K

A61K 31/557 (2006.01) A61K 9/127 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2175896

This invention provides a method of administering an arachidonic acid metabolite, such as prostaglandin E1, to an animal. The metabolite is given to the animal, typically a human, in association with a unilamellar liposome comprising a lipid and a release-inhibiting aqueous buffer. This method can be used to treat animals afflicted with disorders characterized by cell activation and adhesion, inflammation or toxemia.

Cette invention se rapporte à un procédé d'administration d'un métabolite d'acide arachidonique, tel que la prostaglandine E1, à un animal, généralement à un humain, en association avec un liposome unilamellaire contenant un lipide et un tampon aqueux inhibiteur de libération. Ce procédé peut être utilisé pour le traitement d'animaux souffrant de désordres caractérisés par l'activation et l'adhérence des cellules, l'inflammation ou la toxémie.

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