Methods of use of dual ppar agonist compounds and drug...

A - Human Necessities – 61 – K

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Details

A61K 31/40 (2006.01) A61K 31/395 (2006.01) A61L 31/16 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2593483

The present invention relates to uses of dual PPAR agonist compounds and delivery devices containing such compounds. The compounds are useful as pharmaceuticals for the treatment and/or prevention of VSMC proliferation, e.g., stenosis and restenosis, especially restenosis in diabetic patients.

L'invention concerne les utilisations de composés agonistes doubles vis-à-vis des récepteurs PPAR, et des dispositifs de délivrance contenant ces composés, lesquels sont utiles comme produits pharmaceutiques pour le traitement et/ou la prévention de la prolifération des cellules musculaires lisses vasculaires, du type sténose et resténose, en particulier la resténose chez les diabétiques.

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