Methods of use of eggshell polypeptides

A - Human Necessities – 61 – K

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A61K 35/54 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2730664

Identified herem is an active component of chicken eggshells, which is shown ex-vivo studies to have a stimulating effect on bone building cells (osteoblasts) The substance is a polypeptide mixture extracted from eggshells. It has been discovered herein that a composition comprising eggshell polypeptides stimulates osteoblasts, and has osteoinductive /osteogenic properties, hematopoietic properties, and cartilage formation or differentiation properties. The eggshell polypeptide extracts can be locally or systemically administered.

L'invention concerne un composant actif de coquilles d'uf de poule, qui est indiqué dans des études ex vivo comme ayant un effet de stimulation sur des cellules de construction osseuse (ostéoblastes). La substance est un mélange polypeptidique extrait de coquilles d'uf. Il a été découvert qu'une composition comprenant des polypeptides de coquille d'uf stimule les ostéoblastes, et a des propriétés ostéoinductives/ostéogéniques, des propriétés hématopoïétiques, et des propriétés de formation ou de différenciation de cartilage. Les extraits de polypeptide de coquille d'uf peuvent être administrés localement ou systématiquement.

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