Methods of use of phthalocyanines to inactivate blood borne...

A - Human Necessities – 61 – L

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A61L 2/16 (2006.01) A61K 31/40 (2006.01) A61K 31/409 (2006.01) A61K 31/555 (2006.01) A61K 38/06 (2006.01) A61K 41/00 (2006.01) A61L 2/00 (2006.01) A61L 2/08 (2006.01) C12N 7/06 (2006.01)

Patent

CA 2221716

This invention relates to a method for inactivating parasites in blood cell- containing compositions by incubating a mixture of the blood cell-containing composition, a phthalocyanine dye and a quencher and optionally irradiating this mixture with red light. This invention further relates to a method of sterilizing blood cell-containing compositions which contain lipid enveloped viruses and blood home parasites.

L'invention concerne une méthode pour inactiver des parasites dans des compositions contenant des globules sanguins, qui consiste à incuber un mélange d'une composition contenant des globules sanguins, un colorant à la phtalocyanine et un agent d'extinction et éventuellement à irradier ce mélange avec de la lumière rouge. L'invention porte également sur une méthode de stérilisation de compositions contenant des globules sanguins et comprenant des virus enveloppés dans des lipides ainsi que des parasites à diffusion hématogène.

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