Methods of use of trk receptor modulators

Details Methods of use of trk receptor modulators Methods of use of trk receptor modulators

A - Human Necessities

61

K

A61K 38/12 (2006.01) A61K 31/138 (2006.01)

Patent

CA 2671613

The present invention relates to methods of treating or preventing retinal ganglion cell (RGC) death and/or glaucoma using modulators of neurotrophic receptors that comprise .beta.-turn peptidomimetic cyclic compounds or derivatives thereof. The neurotrophic receptor modulators can be used alone, in combination and/or in conjunction with one or more other compounds, molecules or drugs that treat or prevent ocular hypertension, RGC death and/or glaucoma.

L'invention concerne des procédés de traitement ou de prévention de la mort de la cellule ganglionnaire rétinienne (RGC) et/ou du glaucome, en utilisant des modulateurs de récepteurs neurotrophiques, qui comprennent des composés cycliques peptidomimétiques à coude .beta. ou des dérivés de ceux-ci. Les modulateurs de récepteur neurotrophique peuvent être utilisés seuls, en combinaison avec et/ou en même temps qu'un ou plusieurs autres composés, molécules ou médicaments qui traitent ou préviennent l'hypertension oculaire, la mort de la RGC et/ou le glaucome.

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