A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4375 (2006.01) A61K 31/513 (2006.01) A61P 35/02 (2006.01)
Patent
CA 2659861
Methods of treating, preventing or managing hematologic disorders, such as leukemia are disclosed. The methods encompass the administration of SNS-595. Also provided are methods of treatment using this compound with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy. In certain embodiments, the method of treatment comprise administering SNS-595 in combination with Ara-C. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods are also disclosed.
L'invention concerne des procédés de traitement, de prévention ou de gestion de troubles hématologiques, tels que la leucémie. Ces procédés consistent à administrer SNS-595. Elle concerne également des procédés de traitement au moyen de ce composé associés à la chimiothérapie, la radiothérapie, la thérapie hormonale, la thérapie biologique ou l'immunothérapie. Dans certains modes de réalisation, ces procédés consistent à administrer SNS-595 combiné à Ara-C. L'invention concerne également des compositions pharmaceutiques et des formes galéniques unitaires appropriées pour une utilisation avec ces procédés.
Adelman Daniel C.
Michelson Glenn
Scatena Caroline Darne
Silverman Jeffrey A.
Osler Hoskin & Harcourt Llp
Sunesis Pharmaceuticals Inc.
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