A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/366 (2006.01) A61K 31/00 (2006.01) A61K 31/295 (2006.01) A61K 31/335 (2006.01) A61K 31/357 (2006.01) A61K 31/555 (2006.01) A61K 33/26 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2488347
The invention provides methods for preventing or delaying the development of cancer by administering free radical-generating agents to a subject. Representative free radical-generating agents include endoperoxide compounds, such as endoperoxides bearing sesquiterpene compounds such as artemisinin and its analogs, arteflene and its analogs, 1, 2, 4-trioxanes and 1, 2, 4, 5- tetraoxanes. Intracellular iron concentrations may be enhanced by the administration of iron salts or complexes.
L'invention se rapporte à des méthodes permettant de prévenir ou de retarder le développement d'un cancer et consistant à administrer des agents générant des radicaux libres à un sujet. Les agents générateurs de radicaux libres représentatifs incluent les composés endoperoxydes, tels que les endoperoxydes porteurs de composés sesquiterpène tels l'artémisinine et ses analogues, l'artéflène et ses analogues, les 1,2,4-trioxanes et les 1,2,4,5-tétraoxanes. Il est possible d'accroître des concentrations en fer intracellulaire en administrant des sels ou des complexes de fer.
Lai Henry C.
Singh Narendra P.
Mbm Intellectual Property Law Llp
University Of Washington
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