Methods of using gpr119 receptor to identify compounds...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2618488

The present invention relates to methods of using GPR119 receptor to identify compounds useful for increasing bone mass in an individual. Agonists of GPR119 receptor are useful as therapeutic agents for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. Agonists of GPR119 receptor promote bone formation in an individual.

L'invention concerne des procédés d'utilisation du récepteur GPR119 pour identifier des composés qui sont utiles pour augmenter la masse osseuse chez un individu. Des agonistes du récepteur GPR119 sont utilisés comme agents thérapeutiques pour traiter ou prévenir un état caractérisé par une masse osseuse faible, tel que l'ostéoporose, et pour augmenter la masse osseuse chez un individu. Les agonistes du récepteur GPR119 favorisent la formation osseuse chez un individu.

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