Methods of using il-31 to treat airway hyper-responsiveness...

Details Methods of using il-31 to treat airway hyper-responsiveness... Methods of using il-31 to treat airway hyper-responsiveness...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2672739

Use of IL-31 agonists, including IL-31, are used to treat agonists are used to treat asthma, airway hyper-responsiveness or allergic rhinitis. The method comprise inhibiting, reducing, limiting or minimizing production of proimflammatory cytokines and include administration of the IL-31 agonsit during sensitization or challenge resulting in the asthma, airway hyper-responsiveness or allergic rhinitis state.

Des agonistes de IL-31, y compris IL-31, sont utilisés dans le traitement de l'asthme, de l'hyper-réactivité respiratoire ou de la rhinite allergique. La méthode de l'invention consiste à inhiber, limiter ou minimiser la production de cytokines inflammatoires et inclut l'administration d'agonistes de IL-31 au cours de la sensibilisation ou de l'épreuve à l'origine de l'asthme, de l'hyper-réactivité des voies respiratoires ou de la rhinite allergique

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