A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 35/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/715 (2006.01) C12Q 1/00 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2427840
The invention relates to the discovery that IMXP-888, a protein with homology to the FGF receptor family, is a proinflammatory cytokine. The invention encompasses therapeutic compositions of IMXP-888 polypeptides and antagonists, methods of use thereof, and screening methods.
L'invention concerne la découverte qu'IMXP-888, une protéine présentant une homologie avec la famille du récepteur de FGF, est une cytokine proinflammatoire. Cette invention comprend des compositions thérapeutiques de polypeptides d'IMXP-888 et d'antagonistes d'IMXP-888, des procédés d'utilisation de celles-ci, et des procédés de criblage.
Born Teresa L.
Chipman Stewart D.
Dubose Robert F.
Schooley Kenneth A.
Immunex Corporation
Smart & Biggar
LandOfFree
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