Methods of using phhla2 to co-stimulate t-cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 16/42 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C07K 14/725 (2006.01)

Patent

CA 2606334

The invention provides pHHLA2 co-receptor polypeptides and functional fragments, antibodies to same, isolated polynucleotides encoding same, vectors containing the polynucleotides, cells containing the vectors. Methods of making and using these co--stimulatory pHHLA2 co-receptors molecules are also disclosed.

La présente invention concerne des polypeptides co-récepteurs de pHHLA2 et des fragments et des anticorps fonctionnels desdits polypeptides, des polynucléotides isolés les encodant, des vecteurs contenant les polynucléotides, des cellules contenant les vecteurs. L'invention concerne également des procédés de fabrication et d'utilisation de ces molécules co-réceptrices de pHHLA2 co-stimulantes.

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