Methods, probe sets, and kits for detection of deletion of...

Details Methods, probe sets, and kits for detection of deletion of... Methods, probe sets, and kits for detection of deletion of...

C - Chemistry, Metallurgy

40

B

C40B 40/06 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C40B 50/00 (2006.01)

Patent

CA 2696545

Methods, probe sets, kits, and compositions for tumor suppressor gene deletion assays are disclosed. In some embodiments, the methods relate to preparing probes for a deletion assay, performing a deletion assay, or optimizing a deletion assay. In some embodiments, the methods and probe sets can provide reduced artifactual deletion frequency, for example, when analyzing samples subject to truncation artifacts. In some embodiments, the methods and probe sets can distinguish between small and large deletions of tumor suppressor genes.

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